Brain

Nature Reviews Neuroscience, Published online: 25 January 2022; doi:10.1038/s41583-022-00559-8Reproductive state-dependent social behaviours in female mice are governed by the responsiveness of a hypothalamic neuron subtype to male cues

Nature Reviews Neuroscience, Published online: 17 January 2022; doi:10.1038/s41583-022-00557-wTemporarily reducing inhibition in CA1 of the mouse hippocampus enables stimulation-induced over-representation of rewarded locations.

Nature Reviews Neuroscience, Published online: 13 January 2022; doi:10.1038/s41583-021-00548-3Deciphering the mechanisms that cause encoded memories to be forgotten may help us to understand both adaptive forgetting and pathological memory loss. In this Perspective, Tomás Ryan and Paul Frankland propose that forgetting involves neuroplasticity that alters engram cells accessibility and is governed by changes in environmental predictability.

Nature Reviews Neuroscience, Published online: 07 January 2022; doi:10.1038/s41583-021-00555-4Crosstalk between the peripheral nervous system and the immune system coordinates responses to external and internal threats, including pathogens and tissue damage. Chiu and colleagues review our current understanding of the mechanisms by which sensory, sympathetic, parasympathetic and enteric neurons modulate immune cell function.

Nature Reviews Neuroscience, Published online: 04 January 2022; doi:10.1038/s41583-021-00544-7Ingestive and digestive processes are initiated and regulated by mechanosensory signals along the digestive tract. In this Review, Kim, Heo and Kim discuss recent discoveries of specific mechanoreceptors, contributing ion channels and well-defined circuits underlying gut mechanosensation, focusing on the oral and pharyngeal cavities, oesophagus, stomach and intestines.