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gene : a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material — Webster
Gene is a sequence of DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism’s offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.. — Wikipedia
Genetics is the study of genes, genetic variation, and heredity in living organisms. It is generally considered a field of biology, but intersects frequently with many other life sciences and is strongly linked with the study of information systems. — Wikipedia
Genomics is an interdisciplinary field of science focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism’s complete set of DNA, including all of its genes. In contrast to genetics, which refers to the study of individual genes and their roles in inheritance, genomics aims at the collective characterization and quantification of genes, which direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes.[Advances in genomics have triggered a revolution in discovery-based research and systems biology to facilitate understanding of even the most complex biological systems such as the brain. — Wikipedia
Nature Genetics - Issue - nature.com science feeds Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human traits and on other model organisms, including mouse, fly, nematode and yeast. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation.
Long noncoding RNA MALAT1 suppresses breast...
by Jongchan Kim on October 22, 2018 at 12:00 am
Long noncoding RNA MALAT1 suppresses breast cancer metastasisLong noncoding RNA MALAT1 suppresses breast cancer metastasis, Published online: 22 October 2018; doi:10.1038/s41588-018-0252-3Targeted inactivation, restoration and overexpression of MALAT1 in multiple in vivo models demonstrate that the lncRNA MALAT1 suppresses breast cancer metastasis through binding and inactivation of the pro-metastatic transcription factor TEAD. […]
Insights into imprinting from parent-of-origin...
by Florian Zink on October 22, 2018 at 12:00 am
Insights into imprinting from parent-of-origin phased methylomes and transcriptomesInsights into imprinting from parent-of-origin phased methylomes and transcriptomes, Published online: 22 October 2018; doi:10.1038/s41588-018-0232-7Two hundred and eighty-five methylomes and 11,617 transcriptomes from peripheral blood samples with parent-of-origin-phased haplotypes produce a new map of imprinted methylation and gene expression patterns across the human genome. […]
Chromatin run-on and sequencing maps the...
by Tinyi Chu on October 22, 2018 at 12:00 am
Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiformeChromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme, Published online: 22 October 2018; doi:10.1038/s41588-018-0244-3Chromatin run-on and sequencing (ChRO-seq) is a new method that maps the location of RNA polymerase using virtually any input sample. Here, ChRO-seq is used to study nascent transcription in human glioblastoma, and to […]
Single-molecule nascent RNA sequencing identifies...
by Jacob M. Tome on October 22, 2018 at 12:00 am
Single-molecule nascent RNA sequencing identifies regulatory domain architecture at promoters and enhancersSingle-molecule nascent RNA sequencing identifies regulatory domain architecture at promoters and enhancers, Published online: 22 October 2018; doi:10.1038/s41588-018-0234-5Sequencing nascent RNAs at single-molecule resolution with CoPRO unravels the interplay between Pol II initiation, capping and pausing. Transcription start site clusters provide a framework for understanding genome […]
Investigation of inter- and intraspecies...
by Tammi C. Vesth on October 22, 2018 at 12:00 am
Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section NigriInvestigation of inter- and intraspecies variation through genome sequencing of <i>Aspergillus</i> section <i>Nigri</i>, Published online: 22 October 2018; doi:10.1038/s41588-018-0246-1De novo assembly of 23 Aspergillus section Nigri and 6 Aspergillus niger genome sequences allows for inter- and intraspecies comparisons and prediction of secondary metabolite gene […]
Phys.org - latest science and technology news stories Phys.org internet news portal provides the latest news on science including: Physics, Nanotechnology, Life Sciences, Space Science, Earth Science, Environment, Health and Medicine.
Judge slashes award but upholds verdict in...
on October 23, 2018 at 7:20 am
A San Francisco judge on Monday upheld a jury verdict that found Monsanto liable for not warning a groundskeeper that its weed killer product Roundup might cause cancer, but slashed the damages award. […]
Overspending on defense arsenal bankrupts a...
on October 22, 2018 at 7:00 pm
Defend or grow? Can plants do both at the same time? Michigan State University scientists might be inching closer to answering these questions. The answers matter. They could someday help us understand natural ecosystems or help farmers increase yields, without increasing dependence on chemicals to resist pests. […]
Special journal issue looks for new clues about...
on October 22, 2018 at 6:02 pm
Hundreds of millions of years before there was a chicken or an egg to debate, the first complex animals were evolving in parallel with Earth's rising oxygen levels. […]
Spotlighting differences in closely-related...
on October 22, 2018 at 4:55 pm
There are millions of fungal species, and those few hundred found in the Aspergillus genus play important roles in areas ranging from industrial production to agricultural plant pathogens. Reported October 22, 2018, in Nature Genetics, a team led by scientists at the Technical University of Denmark, the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, and the Joint Bioenergy Institute (JBEI), a DOE Bioenergy Research Center, present the first […]
Scientists make new 'green' electronic...
on October 22, 2018 at 4:42 pm
An interdisciplinary team of scientists at the University of Massachusetts Amherst has produced a new class of electronic materials that may lead to a "green," more sustainable future in biomedical and environmental sensing, say research leaders microbiologist Derek Lovley and polymer scientist Todd Emrick. […]